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Recurrent Ovarian Carcinoma Presenting as a Solitary Sternal Metastasis on FDG PET/CT

Ho, Linh MD; Kaushik, Aarti MD; Zhang, Weifang MD; Wassef, Heidi MD

Clinical Nuclear Medicine:
doi: 10.1097/RLU.0b013e31821a26d2
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Abstract

We report the positron emission tomography/computed tomography appearance of solitary sternal metastasis from primary ovarian carcinoma in a 65-year-old woman who underwent surgery followed by chemoradiation treatment 3 years earlier. Restaging positron emission tomography/computed tomography study demonstrates an intensely active destructive lesion involving the entire sternum (maximum standard uptake value: 4.7) with a photopenic soft tissue mass component in the center of the sternum protruding anteriorly suggestive of necrosis. This sternal lesion was subsequently biopsied and pathology revealed metastatic disease from the primary ovarian tumor for which the patient had received chemoradiation therapy. Bone involvement in ovarian cancer is relatively rare and even rarer in the sternum.

Author Information

From the PET Imaging Science Center, Division of Nuclear Medicine, Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA.

Received for publication December 2, 2010; revision accepted January 12, 2011.

Reprints: Linh Ho, MD, University of Southern California, 1510 San Pablo St, Suite 350, Los Angeles, CA 90033. Email: linhho@usc.edu.

© 2011 Lippincott Williams & Wilkins, Inc.