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Pulmonary Artery Sarcoma Detected on F-18 FDG PET/CT as Origin of Multiple Spinal Metastases

Chun, In Kook MD*; Eo, Jae Seon MD*; Paeng, Jin Chul MD*; Kim, Dong Wan MD; Chung, June-Key MD*; Lee, Dong Soo MD*

doi: 10.1097/RLU.0b013e318217ae58
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A 67-year-old man with back pain was diagnosed as having multiple spinal metastases on MRI. On CT scan, only a filling defect in the right pulmonary artery was observed and suspected as venous thromboembolism. On F-18 fluorodeoxyglucose (FDG) PET/CT, intense hypermetabolism was observed in the right pulmonary artery in addition to the metastatic spine lesions. Biopsy confirmed the lesion as a primary pulmonary artery sarcoma (PAS), and the spine lesions as metastases of PAS. Although PAS is rare and its bone metastasis presenting initial symptom is extremely rare, FDG PET/CT is an effective diagnostic modality for PAS, not only in discrimination from venous thromboembolism, but also in workup of metastatic origin.

From the Departments of *Nuclear Medicine and †Internal Medicine, Seoul National University Hospital, Seoul, Korea.

Received for publication September 25, 2010; revision accepted January 8, 2011.

Reprints: Jin Chul Paeng, MD, Department of Nuclear Medicine, Seoul National University Hospital, Daehang-ro 101, Jongno-gu, 110–744, Seoul, Korea. E-mail: paengjc@snu.ac.kr.

© 2011 Lippincott Williams & Wilkins, Inc.