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Vanishing Vertebra

MABILLE, LAURENCE M.D.*; BERENGER, NATHALIE M.D.*; LAREDO, JEAN-DENIS M.D.; KUNTZ, DANIEL M.D.; MUNDLER, OLIVIER M.D.*

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The authors describe a patient who had Gorham-Stout syndrome involving the lumbar spine. This syndrome, which also is called vanishing bone disease or idiopathic massive osteolysis, is a rare and generally unifocal disorder, seen in young adults (about 140 patients reported). Involvement of the lumbar spine is not frequent (3 patients reported) and has a worse prognosis because of late neurological complications. The pathogenesis is incompletely known. The diagnosis is made with biopsy (bony lymphangiomatous changes on microscopy). The clinical evolution is unpredictable. Complications depend on the affected bones (neurological or pulmonary).

From the Department of Nuclear Medicine,* Department of Osteoarticular Radiology, and Department of Rhumatology, Lariboisière Hospital, Paris, France

Received for publication March 19, 1996; accepted April 25, 1996.

Reprint requests: Laurence Mabille, M.D., Department of Nuclear Medicine, Lariboisière Hospital, 2 Rue Ambroise Pare, 75475 Paris Cedex 10, France.

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