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In-111 Octreotide Uptake in Substernal Colloid

SINGH, RAJINDER P. PHD., M.D.; SMITH, GARY T. M.D.; HUBNER, KARL F. M.D.

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In-111 octreotide, a somatostatin analog, has been used for detecting gastrinomas, insulinomas, glucagonomas, apudomas, carcinoids, medullary thyroid carcinomas, lung carcinomas, as well as other malignacies. The case presented is that of a 76-year-old woman with a history of recurrent gastrointestinal bleeding. Endoscopy showed a gastric ulcer. A secretin stimulation test showed positive results and serum gastrin levels were markedly elevated. An In-111 octreotide scan demonstrated increased mediastinal uptake. On thoracotomy, the lesion was identified as a substernal goiter.

From the Department of Radiology, University of Tennessee Medical Center, Knoxville, Tennessee

Received for publication April 25, 1995; revision accepted February 7, 1996.

Reprint requests: Karl F. Hubner, M.D., Professor of Radiology, University of Tennessee Medical Center at Knoxville, 1924 Alcoa Highway, Knoxville, TN 37920.

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