Institutional members access full text with Ovid®

Share this article on:

Citrulline Malate Enhances Athletic Anaerobic Performance and Relieves Muscle Soreness

Pérez-Guisado, Joaquín1; Jakeman, Philip M2

Journal of Strength & Conditioning Research: May 2010 - Volume 24 - Issue 5 - pp 1215-1222
doi: 10.1519/JSC.0b013e3181cb28e0
Original Article

Pérez-Guisado, J and Jakeman, PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res 24(5): 1215-1222, 2010-The purpose of the present study was to determine the effects of a single dose of citrulline malate (CM) on the performance of flat barbell bench presses as an anaerobic exercise and in terms of decreasing muscle soreness after exercise. Forty-one men performed 2 consecutive pectoral training session protocols (16 sets). The study was performed as a randomized, double-blind, 2-period crossover design. Eight grams of CM was used in 1 of the 2 training sessions, and a placebo was used in the other. The subjects' resistance was tested using the repetitions to fatigue test, at 80% of their predetermined 1 repetition maximum (RM), in the 8 sets of flat barbell bench presses during the pectoral training session (S1-4 and S1′-4′). The p-value was 0.05. The number of repetitions showed a significant increase from placebo treatment to CM treatment from the third set evaluated (p <0.0001). This increase was positively correlated with the number of sets, achieving 52.92% more repetitions and the 100% of response in the last set (S4'). A significant decrease of 40% in muscle soreness at 24 hours and 48 hours after the pectoral training session and a higher percentage response than 90% was achieved with CM supplementation. The only side effect reported was a feeling of stomach discomfort in 14.63% of the subjects. We conclude that the use of CM might be useful to increase athletic performance in high-intensity anaerobic exercises with short rest times and to relieve postexercise muscle soreness. Thus, athletes undergoing intensive preparation involving a high level of training or in competitive events might profit from CM.

1Department of Medicine, University of Córdoba, Córdoba, Spain; and 2Department of Physical Education and Sport Sciences, University of Limerick, Limerick, Ireland

Address correspondence to Joaquín Pérez Guisado, pv1peguj@uco.es.

© 2010 National Strength and Conditioning Association