Caruso, JF, Hari, P, Leeper, AE, Coday, MA, Monda, JK, Ramey, ES, Hastings, LP, Golden, MR, and Davison, SW. Impact of acceleration on blood lactate values derived from high-speed resistance exercise. J. Strength Cond Res 23(7): 2009-2014, 2009-Acceleration, or an increase in the rate of movement, is integral to success in many sports. Improvements in acceleration often entail workouts done at intensities that elicit higher blood lactate concentrations (BLa−). The purpose of the study is to assess the impact of acceleration on BLa−. Methods required subjects (n = 45) to perform 4 workouts that each involved two 1-minute sets of hip- and knee-extension repetitions on an inertial exercise trainer (Impulse Training Systems, Newnan, Georgia). Subjects performed 2 workouts comprised solely of phasic or tonic repetitions; their sequence was randomized to prevent an order effect. Before and 5 minutes after exercise, subjects' BLa− were assessed with a calibrated analyzer (Sports Resource Group, Hawthorne, New York). Post and delta (post-pre) BLa− both served as criterion measures for multivariate analysis. Average and peak acceleration values, derived from both phasic and tonic workouts, served as predictor variables. Results showed statistical significance (p < 0.05; R2 = 0.2534) and yielded the following prediction equation from phasic workouts: delta BLa− = 1.40 + 1.116 (average acceleration set 1) - 0.011 (peak acceleration set 1) - 0.634 (average acceleration set 2) + 0.005 (peak acceleration set 2). Conclusions suggest delta BLa− variance, which represents the increase of the metabolite incurred from workouts, is most easily explained by average acceleration values, which describes the mean increase in the rate of movement from phasic workouts. To improve an athlete's tolerance for acceleration-induced BLa− increases, workouts should be tailored with respect to the muscles involved and the duration of exercise bouts of their chosen sport.