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Exercise and Recovery Responses of Lymphokines to Heavy Resistance Exercise.

BUSH, JILL A.; DOHI, KEIICHIRO; MASTRO, ANDREA M.; VOLEK, JEFF S.; LYNCH, J. MICHAEL; TRIPLETT-McBRIDE, N. TRAVIS; PUTUKIAN, MARGOT; SEBASTIANELLI, WAYNE J.; NEWTON, ROBERT U.; HAKKINEN, KEIJO; KRAEMER, WILLIAM J.
Journal of Strength & Conditioning Research: August 2000
Original Article: PDF Only

To examine the effect of dynamic resistance exercise on the response patterns of lymphokines, 10 strength-trained men (21.7 +/- 0.6 y) performed 2 resistance exercise protocols, high force (HF) and high power (HP), of equal total work (HF = 33.0 +/- 2.5 kJ; HP = 33.3 +/- 2.7 kJ) in a randomized order separated by 1 week. Resting blood samples were obtained preexercise and 0 (R-0), 15 (R-15), and 240 (R-240) minutes postexercise. Plasma lactate significantly (p <0.05) increased from baseline for both protocols; however, concentrations were higher in response to the HF protocol. Plasma interleukin-2 (IL-2) concentrations were significantly decreased from baseline at R-15 following the HF protocol. Plasma interfer-on-gamma (IFN-[gamma]) concentrations decreased at R-0 following the HP protocol and returned to preexercise levels by R-15. Although the suppression of these 2 lymphokines was transient, the results indicate that the acute stress of high force and high resistance workouts induce differential IFN-[gamma] and IL-2 responses.

(C) 2000 National Strength and Conditioning Association