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New Therapeutic Targets

Created:   7/10/2012
Contains:  88 items

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Immunoablation Followed by Stem Cell Reconstitution Halts Aggressive MS for Five-Plus Years, But Adverse Events Remain a Concern

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Next-Generation Tissue Implant Offers Noninvasive Drug Delivery and Peers Deep into Neurons

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News from the AAN Annual Meeting: Genome Sequencing in Epilepsy: Lessons Learned, New Therapeutic Targets

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News from the AAN Annual Meeting: Genome Sequencing in Epilepsy: Lessons Learned, New Therapeutic Targets

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News from the AAN Annual Meeting: Antisense Therapy Halts Spinocerebellar Ataxia Disease Progression in Two Mouse Models, Pointing Toward a Clinical Trial

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News from the AAN Annual Meeting: Modified Amino Acid Improves Cerebellar Ataxia in Niemann-Pick Type C, A Case Series Shows

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News from the AAN Annual Meeting: Preclinical Success Reported with Gene Therapy for Spinal Muscular Atrophy

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Two Topical Drugs Found to Promote Functional Remyelination in Cellular Models of Multiple Sclerosis

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A Form of Interferon May Help Keep West Nile Virus from Getting into the Brain, A New Study Suggests

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NEWS FROM THE SOCIETY FOR NEUROSCIENCE ANNUAL MEETING: Zinc Finger and Antisense Methods for Silencing Mutant Huntington's Gene Show Preclinical Success

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VIDEOS ON DEMAND: Spinal Muscular Atrophy: Why a new antisense therapy is moving to phase 3 trials.

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NEWS FROM THE SOCIETY FOR NEUROSCIENCE ANNUAL MEETING: Molecular Mechanism Identified in Sleep Deprivation-Related Memory Loss Raising Level of a Translational Protein in the...

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Human Pain Neurons Developed to Promote New Targets for Improving Analgesics

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A New Model of the Pathology of the JC Virus

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A Cancer Drug Reverses the Effects of a Mutant Causing a Muscular Dystrophy

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Cognitive Behavior Therapy Found to Reduce Psychogenic Non-Epileptic Seizures

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With Extended Monitoring, More Detection of Atrial Fibrillation

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NEWS FROM THE AAN ANNUAL MEETING: HDAC Inhibitor Found Safe and Tolerable for Huntington's Disease in Phase 2 Trial Level of Mutant Huntingtin Changed in the Bloodstream

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Largest Clinical Trial of Three Different Types of Drugs Finds Levodopa Therapy Most Effective to Start for Parkinson's Disease

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Why Investigators are Optimistic about an Immunotherapy for Parkinson's Disease

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How a CNS Infection was Diagnosed in 48 Hours

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NEWS FROM THE AAN ANNUAL MEETING: Exon Skipping for Duchenne Muscular Dystrophy Moves Closer to the Clinic

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NEWS FROM THE AAN ANNUAL MEETING: HDAC Inhibition Appears Safe in Early Trial on Friedreich's Ataxia

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Cysteine Supplementation Reverses Abnormalities in Huntington's Disease Cell and Animal Models

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A Proof of Principle for Reversing Muscle Aging

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Preclinical Success in Two X-Linked Pediatric Diseases Sets Stage for Clinical Trials

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Tactile Feedback Achieved in Bionic Limb

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Novel Gene Discovery Method Implicates New Genes for Hereditary Spastic Paraplegia — Links to Other Neurodegenerative Diseases

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A New Theory — and Brain Areas Implicated — to Explain Dyslexia

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New Therapeutic Target Identified for Leigh Syndrome

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TUNE IN, JOIN IN THE DIALOGUE: Are a new diagnostic blood assay and a novel treatment for inclusion body myositis ready for prime time?

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Nanotechnology Used to Deliver Drug That Targets Glioblastoma Tumors

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PERKy Prion-Infected Mice May Hold Clues to Treating Many Neurodegenerative Diseases

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And a Monoclonal Antibody Treatment Helps with Muscle Volume in sIBM

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NEWS FROM THE ANA ANNUAL MEETING: Blood Test for IBM Shows High Specificity...

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Antisense Therapy Against C9ORF72 Looks Promising in ALS Models

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DARPA Launches $70 Million Neurotechnology Initiative

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NEWS FROM THE ANA ANNUAL MEETING: New Model of Cryptococcal Meningitis Tests Effects of Different Viral Strains

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Exosome Injection Reportedly Enhances Stroke Recovery in Rats

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Few Immune Issues with Dopamine Stem Cell Transplants in Primates

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Stem Cell Defects Associated with Down Syndrome

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The Bionic Limb Gets a Leg Up: Signals to Nerves in Amputated Leg Result in More Fluid Movement

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Genetic Mutations Identified for Multiple-System Atrophy: Mostly Applicable Though To Japanese

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New IOM Report: Why Results from Animal Models Don't Often Translate into Clinical Results

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A New Disease Pathway Is Identified for Spinocerebellar Ataxia — A Screening Strategy That Could Be Used for Other Neurodegenerative Disorders

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What Accounts for ‘Runner's High’ in Humans and Dogs?The Innate Cannabinoid Receptor System Offer Clues

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Got Pruritus? New Neural Pathway Identified to Target the Common Itch

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Two Agents Found to Have Anti-Prion Activity — Experts View the Screening Method as Promising

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Investigators Convert Human Fibroblast into Embryonic Stem Cells

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Novel Technique Generates Oligodendrocyte Precursor Cells

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Moving Forward on a New Therapeutic Target — Oligodendrocytes — for ALS

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NEWS FROM THE AAN ANNUAL MEETING: Should mTOR Inhibitors Replace Surgery as the First-Line Treatment of Tuberous Sclerosis-SEGA?

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Lithium Improves Cognition in Down Syndrome Animal Model: Is It Viable for Human Trials?

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Cell Signaling Defect Is Associated with Neonatal Hydrocephalus: Prenatal Lithium Can Treat It

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Dantrolene Improves Exon Skipping in Duchenne Muscular Dystrophy Models, Raising Hopes for Combination Therapy

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Tadalafil Improves Muscle Oxygenation in Becker Muscular Dystrophy

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Neural Stem Cells Reach Gliomas Intranasally

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New Understanding of Synaptic Scaling Provides Clues to Neurologic Therapy Targets

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New Facioscapulohumeral Dystrophy Mutation Explains FSHD2, and More

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NEWS FROM THE SOCIETY FOR NEUROSCIENCE ANNUAL MEETING: Mutant Huntingtin Protein Suppressed in Animal Model of Huntington's Disease

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Neural Stem Cells Appear to Produce Myelin in Brains of Boys with Rare Genetic Disorder

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NEWS FROM THE AMERICAN NEUROLOGICAL ASSOCIATION ANNUAL MEETING: Turn on a Light, Turn off a Seizure? Optogenetics Comes to Epilepsy

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How Does Myelination Maturation Affect Thought and Behavior?: A Chimp to Human Comparison Offers New Clues

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An Antigen-Specific Technique Halts Myasthenia Gravis in Animal Model: Experts Ask: Could It Work in Humans?

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FDA Approves First Trial of Schwann Cell Transplantation for Spinal Cord Injury

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Amyloid Beta Reverses MS-like Disease in Mice. Is It Time to Re-evaluate Amyloid Elsewhere?

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Can a Growth Hormone-Stimulating Drug Improve Cognitive Function?

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A New Protein Is Implicated in Myotonic Dystrophy, Pointing the Way to a Therapeutic Target

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Two New Mutations Identified as Potential Therapeutic Targets for Glioblastoma Multiforme

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Using Induced Stem Cells from Patients, Scientists Restore Muscle Protein Deficits in Model for Limb Girdle Muscular Dystrophy

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Serum Levels of Antibodies to a Potassium Channel Found Higher in People with MS

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Where the Stem Cell Research Funding Is — State or Federal? Public or Private?

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Silencing MicroRNAs Found to Reduce Seizures in Epilepsy Model: A Potential New Route for Drug Development

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Antisense Therapy Reverses Symptoms in Huntington Model, with Long-term Benefits: Investigators Envision Clinical Trial Within Two Years

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Restoring Locomotion After Spinal Cord Injury: New Study First to Combine Three Therapies

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Fatty Acids Quell Myelin Inflammation in MS model

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Human Stem Cells Generate Normal Muscle Fibers in Mouse Model of Muscular Dystrophy

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Exon Skipping for Duchenne Muscular Dystrophy Clears Another Hurdle

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Antisense Therapy for ALS Found Safe in Small Trial, but More Safety Data Are Sought

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News from the AAN Annual Meeting: Novel Agent Reduces MS. Lesions in Early Trial

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News from the AAN Annual Meeting: Common Inflammatory Pathways Identified for ALS Animal Model and Humans With Disease, Suggesting New Therapeutic Targets

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Hand Function Restored in Paralyzed Monkeys Through Brain-Machine Interface

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Bone Marrow Transplants Arrest Pathology in Mouse Model of Rett Syndrome

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News from the AAN Annual Meeting: Exon-skipping Therapy Moves Forward in Duchenne Muscular Dystrophy Trials

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Systemic Administration of Antisense Therapy for Duchenne Dystrophy Found Safe, Possibly Effective

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In the Lab with Dr. Samuel Pfaff — The Search for Stem Cell Cures

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Antisense Therapy for Myotonic Dystrophy Seen As Promising Inroad

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HD Protein Cleared in Animal Model: Approach Could Apply to Other Neurodegenerative Diseases

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