Intraoperative video obtained prior to resection of a right parietal glioblastoma. The screen displays dual ultrasound imaging of the same field of view with low MI US B-mode imaging on the left hand side and iCEUS imaging on the right hand side of the screen. Standard B-mode US allows identification of the region of interest while iCEUS is performed. On the left inferior corner is also visible a timer, which is manually started after UCA injection and permits the evaluation of the different vascular phases. Note how iCEUS is able to show the dynamic perfusion of the lesion, highlighting major feeding vessels, intralesion arteries, tumor mass, cystic/necrotic areas and draining veins. iCEUS degree of enhancement of the lesion is compared to normal brain parenchyma CE.