ZUSMAN, EDIE E.
Neurosurgery. 66(4):N14-N15, April 2010.
doi: 10.1227/01.neu.0000369893.26668.6a
ANDERSON, WILLIAM S.
Neurosurgery. 66(4):N15-N16, April 2010.
doi: 10.1227/01.neu.0000369894.03797.75
RAHME, RUDY J.; BATJER, H. HUNT; BENDOK, BERNARD R.
Neurosurgery. 66(4):N16-N17, April 2010.
doi: 10.1227/01.neu.0000369895.11420.56
HOFSTETTER, CHRISTOPH P.; BOOCKVAR, JOHN A.
Neurosurgery. 66(4):N17-N18, April 2010.
doi: 10.1227/01.neu.0000369896.49538.63
CHI, JOHN H.
Neurosurgery. 66(4):N18, April 2010.
doi: 10.1227/01.neu.0000369897.57162.44
LIN, NING; FRIEDLANDER, ROBERT M.
Neurosurgery. 66(4):N19-N20, April 2010.
doi: 10.1227/01.neu.0000369898.34291.27
KOMOTAR, RICARDO J.; STARKE, ROBERT M.; SISTI, MICHAEL B.; CONNOLLY, E. SANDER
Neurosurgery. 66(4):N20-N21, April 2010.
doi: 10.1227/01.neu.0000369899.41915.67
POWERS, CIARAN J.; DEMPSEY, ROBERT J.
Neurosurgery. 66(4):N22-N23, April 2010.
doi: 10.1227/01.neu.0000369900.80032.67
PARR, ANN M; WANG, MICHAEL Y
Neurosurgery. 66(4):N23-N24, April 2010.
doi: 10.1227/01.neu.0000369901.07849.4a
ZENONOS, GEORGIOS; KIM, JEONG EUN
Neurosurgery. 66(4):N24-N25, April 2010.
doi: 10.1227/01.neu.0000369902.53590.c3
Oyesiku, Nelson M
Neurosurgery. 66(4):629, April 2010.
doi: 10.1227/01.neu.0000369903.30720.92
Ferris, Lorraine E.; Fletcher, Robert H.
Neurosurgery. 66(4):629-630, April 2010.
doi: 10.1227/01.neu.0000369904.38343.e4
Huttunen, Terhi; von und zu Fraunberg, Mikael; Frösen, Juhana; Lehecka, Martin; Tromp, Gerard; Helin, Katariina; Koivisto, Timo; Rinne, Jaakko; Ronkainen, Antti; Hernesniemi, Juha; Jääskeläinen, Juha E.
Neurosurgery. 66(4):631-638, April 2010.
doi: 10.1227/01.NEU.0000367634.89384.4B
Chang, Steve W.; Kakarla, Udaya K.; Maughan, Peter H.; DeSanto, Jeff; Fox, Douglas; Theodore, Nicholas; Dickman, Curtis A.; Papadopoulos, Stephen; Sonntag, Volker K.H.
Neurosurgery. 66(4):639-647, April 2010.
doi: 10.1227/01.NEU.0000367449.60796.94
Ducruet, Andrew F.; Hickman, Zachary L.; Zacharia, Brad E.; Grobelny, Bartosz T.; Narula, Reshma; Guo, Kuang-Hua; Claassen, Jan; Lee, Kiwon; Badjatia, Neeraj; Mayer, Stephan A.; Connolly, E. Sander Jr
Neurosurgery. 66(4):648-655, April 2010.
doi: 10.1227/01.NEU.0000360374.59435.60
De Ridder, Dirk; Vanneste, Sven; Adriaenssens, Ine; Lee, Alison Po Kee; Plazier, Mark; Menovsky, Tomas; van der Loo, Elsa; Van de Heyning, Paul; Møller, Aage
Neurosurgery. 66(4):656-660, April 2010.
doi: 10.1227/01.NEU.0000366110.87836.53
Skeie, Bente Sandvei; Enger, P. Ø.; Skeie, G. O.; Thorsen, F.; Pedersen, P-H.
Neurosurgery. 66(4):661-669, April 2010.
doi: 10.1227/01.NEU.0000366112.04015.E2
Jian, Feng-Zeng; Chen, Zan; Wrede, Karsten H.; Samii, Madjid; Ling, Feng
Neurosurgery. 66(4):678-687, April 2010.
doi: 10.1227/01.NEU.0000367632.45384.5A
On the Cover Game theory is a branch of applied mathematics used in social sciences to mathematically capture behavior in strategic situations. The diagram on the cover represents the Nash Equilibrium, a solution concept of a game involving two or more players, in which each player is assumed to know the equilibrium strategies of the other players, and no player has anything to gain by changing only his or her own strategy unilaterally.
Levi, Allan D.; Casella, Gizelda; Green, Barth A.; Dietrich, W. Dalton; Vanni, Steven; Jagid, Jonathan; Wang, Michael Y.
Neurosurgery. 66(4):670-677, April 2010.
doi: 10.1227/01.NEU.0000367557.77973.5F
BACKGROUND: Although a number of neuroprotective strategies have been tested after spinal cord injury (SCI), no treatments have been established as a standard of care. OBJECTIVE: We report the clinical outcomes at 1-year median follow-up, using endovascular hypothermia after SCI and a detailed analysis of the complications. METHODS: We performed a retrospective analysis of American Spinal Injury Association and International Medical Society of Paraplegia Impairment Scale (AIS) scores and complications in 14 patients with SCI presenting with a complete cervical SCI (AIS A). All patients were treated with 48 hours of modest (33°C) intravascular hypothermia. The comparison group was composed of 14 age- and injury-matched subjects treated at the same institution. RESULTS: Six of the 14 cooled patients (42.8%) were incomplete at final follow-up (50.2 [9.7] weeks). Three patients improved to AIS B, 2 patients improved to AIS C, and 1 patient improved to AIS D. Complications were predominantly respiratory and infectious in nature. However, in the control group, a similar number of complications was observed. Adverse events such as coagulopathy, deep venous thrombosis, and pulmonary embolism were not seen in the patients undergoing hypothermia. CONCLUSION: This study is the first phase 1 clinical trial on the safety and outcome with the use of endovascular hypothermia in the treatment of acute cervical SCI. In this small cohort of patients with SCI, complication rates were similar to those of normothermic patients with an associated AIS A conversion rate of 42.8%.
Hasegawa, Toshinori; Kobayashi, Tatsuya; Kida, Yoshihisa
Neurosurgery. 66(4):688-695, April 2010.
doi: 10.1227/01.NEU.0000367554.96981.26
OBJECTIVE: To determine the limiting dose to the optic apparatus in single-fraction irradiation in patients with craniopharyngioma treated with gamma knife radiosurgery (GKRS). METHODS: One hundred patients with 109 craniopharyngiomas treated with GKRS were evaluated with a median follow-up period of 68 months. Tumor volume varied from 0.1 to 36.0 (median, 3.3) cm3. Marginal doses varied from 10 to 18 (median, 11.4) Gy. Maximum dose to any part of the optic apparatus varied from 2 to 18 (median, 10) Gy. RESULTS: The actuarial 5- and 10-year overall rates of survival of tumor progression after GKRS were 93% and 88%, respectively. Similarly, the actuarial 5- and 10-year progression-free survival rates were 62% and 52%, respectively. Among 94 patients in whom visual function was evaluable after GKRS, only 3 patients developed radiation-induced optic neuropathy, indicating an overall Kaplan-Meier radiation-induced optic neuropathy rate of 5%. Of these patients, 2 received 15 Gy or greater to the optic apparatus. Another patient who received 8 Gy or less had undergone previous fractionated radiation therapy with a biologically effective dose of 60 Gy. CONCLUSION: The optic apparatus seems to be more tolerant of irradiation than previously thought. Careful dose planning is essential, particularly in patients who underwent prior external beam radiation therapy.
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