Video of a digital subtraction angiography series showing the effects of implantation of one or more pipeline stents on aneurysm hemodynamics. First, a sidewall aneurysm with a straight parent vessel prior to implantation of a flow diverter stent is shown. A turbulent, circulating, high velocity intra-aneurysmal flow profile can be seen, indicative of high wall shear stress. After implantation of a single stent a reduction of total contrast inflow and time until maximum contrast density is reached. In addition, the turbulent high-velocity aneurysm inflow is scrambled. After superimposition of a second pipeline embolization device a further decrease of inflow-speed and intra-aneurysmal contrast is observed.
Next, digital subtraction angiography series of a fusiform aneurysm model before and after implantation of FDS are shown. Before treatment, a straddling turbulent flow pattern is visualized at the distal aneurysm wall along the outflow tract. After telescoping implantation of two stents contrast flow into the aneurysm is reduced and a pulsatile pattern of contrast inflow through the stent mesh can be seen. Consequently, a reduction in total contrast inflow and time until maximum contrast density is reached. After superimposition of a third pipeline embolization device the contrast agent more homogeneously oozes out of the stent lumen into the aneurysm.