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doi: 10.1227/NEU.0000000000000513

Surgery of Intradural Extramedullary Tumors: Retrospective Analysis of 107 Cases.

Tarantino, Roberto MD; Donnarumma, Pasquale MD; Nigro, Lorenzo MD; Rullo, Marika Ph.D.; Santoro, Antonio MD; Delfini, Roberto MD

Published Ahead-of-Print
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Background: IntraDural ExtraMedullary Tumors (IDEMTs) are uncommon lesions that cause pain and neurological deficits.

Objective: To evaluate the effects of surgery for IDEMTs.

Methods: Cohort study recruiting all patients operated for IDEMTs at the Department of Neurology and Psychiatry of "Sapienza" University of Rome from January 2003 to January 2013. The analysis was conducted on clinical records evaluation over one-year follow-up. The Graphic Rating Scale (GRS) was used for the assessment of pain. Neurological deficits were detected though neurological exam. Quality of life was evaluated with the EuroQol (EQ-5D). Statistical interpretation of the data was performed using SPSS v19 software.

Results: 107 patients were recruited. Three were lost to follow-up. Patients reported lower level of pain one year after surgery (pre-surgery = 6.05, post-surgery = 3.65). Mean comparison showed a significant decrease of [DELTA]= -2.400 (p <.001). 92 (88.5%) patients were neurologically asymptomatic one year after surgery. Only 12 (11.5%) presented with a deficit, with a global decrease of 39% (Chi-square 27.6, p <.005). The quality of life in patients was middle-high (mean rating EQ-5D VAS 61.78 %). The lowest levels of quality of life were found in patients with sphincters dysfunctions (mean= 33.4).

Conclusion: Surgery of IDEMTs has a good outcome. Patients reported lower levels of pain and a drastic reduction of neurological symptoms one year after surgery. The quality of life is middle-high. It is influenced mainly by the neurological outcome.

Copyright (C) by the Congress of Neurological Surgeons


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