BACKGROUND: Technological advances have resulted in diminishing perioperative complications reported during carotid artery stenting (CAS) trials. Because trial experience lags behind technological advances, an understanding of the incidence of perioperative complications after CAS remains in flux.
OBJECTIVE: In this single-arm, observational study, a contemporary experience of CAS at a high-volume academic training center for neuroendovascular surgeons was reviewed to assess perioperative morbidity.
METHODS: A prospectively maintained database of all neuroendovascular procedures was queried for all CAS procedures performed for stenotic atherosclerotic disease between 2009 and 2011. Each case was assessed for major perioperative (30 day) adverse events, including new acute ischemic stroke, postoperative symptomatic intracranial hemorrhage, myocardial infarction (MI), and mortality.
RESULTS: A total of 474 patients were identified. Perioperative adverse events were noted in 13 patients (2.7%). These included 4 ischemic strokes, 4 intracranial hemorrhages, 3 MIs, and 5 deaths. Most perioperative events occurred in symptomatic patients (10 of 239 symptomatic patients with events, 4.2% event incidence), whereas these events occurred rarely in asymptomatic patients (3 of 235 asymptomatic patients with events, 1.3% event incidence).
CONCLUSION: In this retrospective analysis of consecutive patients treated with CAS, the perioperative incidence of stroke (0.9%), MI (0.6%), and death (1.1%) was favorable.
ABBREVIATIONS: CAS, carotid artery stenting
CEA, carotid endarterectomy
CREST, Carotid Revascularization Endarterectomy versus Stenting Trial
MI, myocardial infarction
NASCET, North American Symptomatic Carotid Endarterectomy Trial
NIHSS, National Institutes of Health Stroke scale
*Department of Neurosurgery and Toshiba Stroke and Vascular Research Center, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York;
‡Department of Neurosurgery, Gates Vascular Institute, Kaleida Health, Buffalo, New York;
§Department of Radiology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York;
‖Department of Neurology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York;
¶Jacobs Institute, Buffalo, New York
Correspondence: Adnan H. Siddiqui, MD, PhD, University at Buffalo Neurosurgery, 100 High St, Suite B4, Buffalo New York 14203. E-mail: email@example.com
Received January 10, 2013
Accepted June 27, 2013