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Neuroreport:
16 November 1998 - Volume 9 - Issue 16 - p 3571-3575
Clinical Neuroscience

Alteration of digital representations in somatosensory cortex in focal hand dystonia

Elbert, Thomas; Candia, Victor; Altenmüller, Eckart; Rau, Harald; Sterr, Annette; Rockstroh, Brigitte; Pantev, Christo; Taub, Edward

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Abstract

FOCAL hand dystonia involves a loss of motor control of one or more digits; it is associated with the repetitive, synchronous movements of the digits made by musicians over periods of many years. Magnetic source imaging revealed that there is a er distance (fusion) between the representations of the digits in somatosensory cortex for the affected hand of dystonic musicians than for the hands of non-musician control subjects. The data suggest that use-dependent susceptibility to digital representation fusion in cortex may be involved in the etiology of focal dystonia. A successful therapy for the condition has been developed based on this consideration.

© 1998 Lippincott Williams & Wilkins, Inc.

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