Skip Navigation LinksHome > May 15, 2000 - Volume 11 - Issue 7 > A thalamo‐prefrontal system for representation in executive...
Cognitive Neuroscience

A thalamo‐prefrontal system for representation in executive response choice

Scott, Sophie K.; Holmes, Andy; Friston, Karl J.; Wise, Richard J. S.

Collapse Box


This study demonstrates the neural system potentially involved in the representation of, and choice between, stimulus classifications in an ambiguous, novel, decision‐making task. This difficult choice behaviour is taken as an example of a basic executive processing task. Subjects heard sounds that were consonant‐vowel combinations that had been distorted and were required to categorize each stimulus as speech‐like or not‐speech‐like. Cerebral activity was measured with positron emission tomography. A neural system (thalamic and medial prefrontal cortical regions) was demonstrated; there was greater activity involved in assigning the sound to the larger class of not‐speech‐like sounds than to the more restricted category of speech‐like sounds. We interpret this activity as reflecting process and representation in a simple central executive task.

© 2000 Wolters Kluwer Health | Lippincott Williams & Wilkins


Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.