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Somatosensory areas in man activated by moving stimuli: cytoarchitectonic mapping and PET

Bodegård, Anna1,4; Geyer, Stefan2; Naito, Eiichi1; Zilles, Karl2,3; Roland, Per E.1

Brain Imaging

This study was performed to identify neuronal populations in the somatosensory areas engaged in discrimination of moving stimuli on the skin. Changes in regional cerebral blood flow (rCBF) were measured with positron emission tomography (PET) and correlated with cytoarchitectonic sensorimotor areas 4a, 4p, 3a, 3b, and 1. Volunteers discriminated differences in the speed of a rotating brush stimulating the palmar surface. Discrimination of moving stimuli, contrasted to rest, increased the rCBF mainly in primary somatosensory (S1) area 1, but also in area 3b. The parietal operculum (PO) was activated bilaterally. We conclude that area 1 is the area in S1 which is mainly responding to discrimination of moving stimuli and that the PO contains several regions engaged in the discrimination of fast transient stimuli.

1Division of Human Brain Research, Department of Neuroscience, Doktorsringen 12, Karolinska Institute, S 171 77 Stockholm, Sweden

2Department of Neuroanatomy and C. and O. Vogt Institut für Hirnforschung, Heinrich Heine Universität, Box 101007, 40001 Düsseldorf

3Institute of Medicine, Research Center Jülich, 52425 Jülich, Germany

4Corresponding Author: Anna Bodegård

Acknowledgments: This research was supported by a Biotech grant from the European Commission, by a grant from the Medical Research Council of Sweden and by a grant from Deutsche Forschungsgemeinschaft.

Received 6 October 1999; accepted 3 November 1999

© 2000 Lippincott Williams & Wilkins, Inc.