Enter your Email address:
Wolters Kluwer Health may email you for journal alerts and information, but is committed
to maintaining your privacy and will not share your personal information without
You currently have no recent searches
Knopman, David S. M.D.
David S. Knopman, M.D., is professor of neurology at the Mayo Clinic College of Medicine in Rochester, MN.
DO YOU HAVE A QUESTION TO ASK THE EXPERTS? Send it to firstname.lastname@example.org
Q Does depression increase the risk of dementia?
DR. DAVID S. KNOPMAN RESPONDS:
A Technically, the answer is yes, but not in the way you might think. Depression as a biological disorder does not seem to trigger changes in the brain that make a person more likely to develop Alzheimer's disease or another degenerative brain disorder. Instead, the presence of depression in a person in late mid-life or older age may actually be one of the first signs of dementia. Depression can be caused by many things other than an underlying dementia, but a number of studies have shown that people with depression in late life have an increased risk of becoming demented.
If the question concerns depression in early life or young adulthood, the answer is probably no. But this has been a more difficult question to address and challenging to study. People with severe mental illness in young adulthood often have subsequent life circumstances that are unfavorable, such as low socioeconomic status, complications from medications, prolonged hospitalizations, social isolation, or great interpersonal upheaval. Thus, people with early life depression also have many other factors that contribute to risk for dementia apart from the depression itself.
©2009 American Academy of Neurology
Friend's E-mail is Invalid
Your Name: (optional)
Separate multiple e-mails with a (;).
Thought you might appreciate this item(s) I saw at Neurology Now.
Send a copy to your email
Your message has been successfully sent to your friend.
Some error has occurred while processing your request. Please try after some time.
An Existing Folder
A New Folder
The item(s) has been successfully added to "".
Login with your LWW Journals username and password.
Username or Email:
Enter and submit the email address you registered with. An email with instructions to reset your password will be sent to that address.
Link to reset your password has been sent to specified email address.
What does "Remember me" mean?
By checking this box, you'll stay logged in until you logout. You'll get easier access to your articles, collections,
media, and all your other content, even if you close your browser or shut down your
To protect your most sensitive data and activities (like changing your password),
we'll ask you to re-enter your password when you access these services.
What if I'm on a computer that I share with others?
If you're using a public computer or you share this computer with others, we recommend
that you uncheck the "Remember me" box.
Save my selection