Enter your Email address:
Wolters Kluwer Health may email you for journal alerts and information, but is committed
to maintaining your privacy and will not share your personal information without
You currently have no recent searches
Argoff, Charles E. M.D.
Charles E. Argoff, M.D., is director of the Cohn Pain Management Center at the North Shore University Hospital in Long Island, NY and assistant professor of neurology at the New York University School of Medicine in New York City.
Q Are there drugs to control the unbearable pain of trigeminal neuralgia?
A Several different types of medications provide pain relief, although not all medications are equally effective or well tolerated. Most of the medications are also used for the treatment of epilepsy and are commonly referred to as anti-epileptic medications.
For more than 40 years, studies have shown that carbamazepine (Tegretol) may be effective at reducing the frequency and severity of painful episodes due to trigeminal neuralgia. The downside includes side effects such as bone marrow suppression and liver dysfunction, both of which require careful and ongoing monitoring.
Less rigorously studied has been oxcarbazepine (Trileptal). This medication may be just as good at carbamazepine at reducing the number of pain attacks, but the studies were not placebo-controlled and so it is more difficult to interpret the results. Another drug, lamotrigine, is effective for reducing pain when added to an already established medical regimen for trigeminal neuralgia. In addition, small studies have suggested that other anti-epileptic medications including gabapentin (Neurontin), clonazepam (Klonopin), and valproic acid may have some benefit.
The main thing is to consult with your neurologist to determine the best regimen for you.
©2007 American Academy of Neurology
Friend's E-mail is Invalid
Your Name: (optional)
Separate multiple e-mails with a (;).
Thought you might appreciate this item(s) I saw at Neurology Now.
Send a copy to your email
Your message has been successfully sent to your friend.
Some error has occurred while processing your request. Please try after some time.
An Existing Folder
A New Folder
The item(s) has been successfully added to "".
Login with your LWW Journals username and password.
Username or Email:
Enter and submit the email address you registered with. An email with instructions to reset your password will be sent to that address.
Link to reset your password has been sent to specified email address.
What does "Remember me" mean?
By checking this box, you'll stay logged in for
days or until you logout. You'll get easier access to your articles, collections,
media, and all your other content, even if you close your browser or shut down your
To protect your most sensitive data and activities (like changing your password),
we'll ask you to re-enter your password when you access these services.
What if I'm on a computer that I share with others?
If you're using a public computer or you share this computer with others, we recommend
that you uncheck the "Remember me" box.
Save my selection