Vitamin A insufficiency in obese Egyptian children with dyslipidemia

Ismail, Nagwa A.a; Shatla, Hamed M.c; Nour Eldin, Abeer M.a; Eldeeb, Marwa T.c; Wahbee, Aliaa A.b; Ali, Mohamed E.a

Medical Research Journal:
doi: 10.1097/01.MJX.0000450145.72443.bb
Original Articles
Abstract

Objective: The aim of this article was to focus on vitamin A level in obese children compared with normal controls and to determine the relation between levels of retinol with lipid profile and an inflammation marker.

Participants and methods: Thirty obese and 30 normal weight children, who served as controls, were included in our study. All were subjected to clinical and anthropometric evaluation. Laboratory assessment of high-sensitivity C-reactive protein and lipid profile was performed. Vitamin A levels were quantified.

Results: Results related to lipid profiles and vitamin A levels revealed that low-density lipoprotein, cholesterol, and triglycerides were highly significantly higher in cases than in controls (P<0.001), whereas vitamin A was statistically significantly lower in cases (P=0.000). Correlations between plasma vitamin A and the studied variables showed negative correlation with weight (kg), low-density lipoprotein, and cholesterol, whereas there was a positive correlation between plasma vitamin A and triglyceride level.

Conclusion: Our results revealed that obese children tend to have hyperlipidemia and vitamin A insufficiency compared with their nonobese counterparts. We recommend nutritional education about vitamin A and control of body weight through various means as remedial measures.

Author Information

Departments of aPediatrics

bClinical and Chemical Medicine, National Research Center

cDepartment of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt

Correspondence to Abeer M. Nour Eldin, MD, Department of Pediatrics, National Research Centre, El-Bohouth Street, Dokki, PO Box 2311, Cairo, Egypt Tel: +20 111 844 0787; e-mail: abeernour2012@hotmail.com

Received March 20, 2014

Accepted May 4, 2014

© 2014 Medical Research Journal