Medical Research Journal

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Medical Research Journal:
doi: 10.1097/
Original Articles

Vitamin A insufficiency in obese Egyptian children with dyslipidemia

Ismail, Nagwa A.a; Shatla, Hamed M.c; Nour Eldin, Abeer M.a; Eldeeb, Marwa T.c; Wahbee, Aliaa A.b; Ali, Mohamed E.a

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Objective: The aim of this article was to focus on vitamin A level in obese children compared with normal controls and to determine the relation between levels of retinol with lipid profile and an inflammation marker.

Participants and methods: Thirty obese and 30 normal weight children, who served as controls, were included in our study. All were subjected to clinical and anthropometric evaluation. Laboratory assessment of high-sensitivity C-reactive protein and lipid profile was performed. Vitamin A levels were quantified.

Results: Results related to lipid profiles and vitamin A levels revealed that low-density lipoprotein, cholesterol, and triglycerides were highly significantly higher in cases than in controls (P<0.001), whereas vitamin A was statistically significantly lower in cases (P=0.000). Correlations between plasma vitamin A and the studied variables showed negative correlation with weight (kg), low-density lipoprotein, and cholesterol, whereas there was a positive correlation between plasma vitamin A and triglyceride level.

Conclusion: Our results revealed that obese children tend to have hyperlipidemia and vitamin A insufficiency compared with their nonobese counterparts. We recommend nutritional education about vitamin A and control of body weight through various means as remedial measures.

© 2014 Medical Research Journal


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