Clinical Scenario: Andrea, a 53-year-old postmenopausal woman, is concerned about her loss of desire for sexual activity. Her last menstrual period occurred 2 years ago, and she has experienced minimal vasomotor symptoms. She has a loving relationship with her husband, to whom she has been married for 5 years and with whom she has previously enjoyed sexual intimacy, often initiating it. She is disturbed by the fact that not only has she no sexual desire but also that she has become unresponsive to her husband’s sexual advances. The problem predates menopause by 1 to 2 years. She has recently heard that testosterone may be a treatment for this and wants to know what options are available.