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Body mass index, urinary incontinence, and female sexual dysfunction: how they affect female postmenopausal health

Pace, Gianna MD1,2,3; Silvestri, Vanuska MD2,3; Gualá, Luana MD2,3; Vicentini, Carlo MD, FP2,3

doi: 10.1097/gme.0b013e3181a6b491
Articles

Objective: The aim of this study was to evaluate the relationship between body mass index (BMI) and female sexual dysfunction (FSD) among perimenopausal and postmenopausal women with urinary incontinence (UI).

Methods: From 2005 to 2008, we enrolled 208 consecutive women affected by UI; all underwent a comprehensive history including two validated questionnaires, physical examination, and urodynamic evaluation. Based on BMI, participants were grouped into normal weight, overweight, and obese.

Results: A total of 158 participants completed both questionnaires (76% response rate); 41 (26%) were normal weight, 73 (46%) were overweight, and 44 (28%) were obese. The increasing Urogenital Distress Inventory score had a direct correlation with age (P < 0.01), year of menopause onset (P < 0.05), and BMI (P < 0.01). FSD was diagnosed in 97 women (61%): 31 (32%) with hypoactive sexual desire, 20 (21%) with sexual arousal disorder, 7 (7%) with orgasmic deficiency, and 39 (40%) with sexual pain disorder. BMI greater than 30 kg/m2 was independently associated with an increased risk of FSD (odds ratio [OR], 2.02) and UI (OR, 2.03). With adjustment for BMI, the OR for FSD was 1.22 for overweight women and 1.56 for obese women, with respect to healthy participants. The total Female Sexual Function Index score correlated with BMI (r = −0.82, P = 0.0001); in particular, arousal (r = −0.82), orgasm (r = −0.72), lubrication (r = −0.61), and satisfaction (r = −0.63, all P < 0.001) showed an inverse correlation with BMI, whereas desire and pain did not.

Conclusions: Increased BMI early in menopause represents a risk both for UI and for sexual dysfunction. Weight control has an essential role in postmenopause and should be considered early in perimenopause to safeguard female quality of life as well as to prevent or improve UI and female sexual dysfunction symptoms.

An increased body mass index in the perimenopause represents a risk both for urinary incontinence and for sexual dysfunction. Weight control has an essential role to safeguard female quality of life as regards urinary incontinence and female sexual dysfunction symptom onset and should be considered early in perimenopause.

From the Departments of 1Surgical Sciences and 2Health Sciences, University of L'Aquila, L'Aquila; and 3Department of Urology, Mazzini Hospital, Teramo, Italy.

Received February 3, 2009; revised and accepted March 23, 2009.

Financial disclosure/conflicts of interests: none reported.

Address correspondence to: Gianna Pace, MD, Department of Health Sciences, University of L'Aquila, San Salvatore St., Palace 6 A, Coppito, 67100 L'Aquila, Italy. E-mail: giannapace@gmail.com

©2009The North American Menopause Society