Objective: The aim of this study was to investigate the role of vasomotor and mood symptoms on insomnia in postmenopausal women.
Methods: One hundred sixty-three postmenopausal women, not receiving hormone therapy, attending a menopause clinic at the University of Athens, Greece, were included in this cross-sectional study. Climacteric symptoms were assessed by Greene's scale, whereas psychological morbidity was measured by Zung Self-Assessment Depression Scale, Symptom Checklist-90-R, and Athens Insomnia Scale.
Results: Vasomotor symptoms were significantly associated with insomnia (P = 0.001). When depressive symptomatology was added to the logistic regression analysis, the predictive ability of the model was significantly improved as defined by the increase in the log likelihood (P < 0.001) and the increase in the area under the receiver operating characteristic curve.
Conclusions: Insomnia in postmenopausal women attending a menopause clinic is related both to the effects of vasomotor symptoms and depressive symptomatology. Mood symptoms seem to affect sleep independently of vasomotor symptoms, suggesting that depression should be carefully assessed and treated in postmenopausal women with insomnia.
In postmenopausal women attending a menopause clinic, depressive symptomatology seems to affect sleep independently of vasomotor symptoms, suggesting that depression should be carefully assessed and treated in postmenopausal women with insomnia.
From the 1Women's Mental Health Clinic; 2IPT Unit, First Department of Psychiatry, Eginition Hospital; and 3Menopause Clinic, Second Department of Obstetrics and Gynecology, Aretaieion Hospital, Athens University Medical School, Athens, Greece; 4Department of Counseling and Clinical Psychology, Teachers College; and 5College of Physicians and Surgeons, Columbia University, New York, NY; and 6Sleep Research Unit, First Department of Psychiatry, Eginition Hospital, Athens University Medical School, Athens, Greece.
Received October 8, 2008; revised and accepted November 19, 2008.
Financial disclosure/conflicts of interest: None reported.
Address correspondence to: Areti C. Spyropoulou, MD, Mphil, Women's Mental Health Clinic, First Department of Psychiatry, Eginition Hospital, 74 Vas Sofias Ave, 11528 Athens, Greece. E-mail: email@example.com