Enter your Email address:
Wolters Kluwer Health may email you for journal alerts and information, but is committed
to maintaining your privacy and will not share your personal information without
You currently have no recent searches
Dermatology Department, National Photodermatology Investigative Unit, Ireland
Cutaneous carcinoma is most common in the white skinned peoples of the world. Skin cancer has a direct relationship with exposure to ultraviolet radiation. There are direct links to genetic syndromes which diminish DNA repair capacity. Drugs which interfere with immune surveillance and interfere with mechanisms to eradicate DNA mutations also confer risk of skin cancer. Drugs which photosensitise also are increasingly linked to skin cancer prevalence. Human papilloma virus (HPV) of high risk type is undoubtedly linked with skin cancer in the anogenital regions and rarely with periungual carcinomas. Genital high risk HPV has mechanisms well proved to be carcinogenic. Medium risk HPV is less well characterized but in the genetic disorder epidermodysplasia verruciformis is known to be a co-carcinogen together with UVR. Less definite evidence exists for the various HPV types linked with immunosuppression, some evidence indicates that such HPV may be co-carcinogenic assisting UVR to predispose to skin cancers. Skin cancer comes about from many interconnected mechanisms the relative importance of HPV is slowly being elucidated.
© 2010 Lippincott Williams & Wilkins, Inc.
Colleague's E-mail is Invalid
Your Name: (optional)
Separate multiple e-mails with a (;).
Thought you might appreciate this item(s) I saw at Melanoma Research.
Send a copy to your email
Your message has been successfully sent to your colleague.
Some error has occurred while processing your request. Please try after some time.
An Existing Folder
A New Folder
The item(s) has been successfully added to "".
Login with your LWW Journals username and password.
Username or Email:
Enter and submit the email address you registered with. An email with instructions to reset your password will be sent to that address.
Link to reset your password has been sent to specified email address.
What does "Remember me" mean?
By checking this box, you'll stay logged in until you logout. You'll get easier access to your articles, collections,
media, and all your other content, even if you close your browser or shut down your
To protect your most sensitive data and activities (like changing your password),
we'll ask you to re-enter your password when you access these services.
What if I'm on a computer that I share with others?
If you're using a public computer or you share this computer with others, we recommend
that you uncheck the "Remember me" box.
Save my selection