Study Protocol FAQ

​​Why publish study protocols?
Study protocols provide a detailed blueprint for upcoming clinical trials and Medicine® believes publishing registered trials will help improve the standard of medical research. Study protocols enable more information to be available on current studies, while promoting collaboration and helping to prevent unnecessary duplication of work.

What are the criteria for publishing a study protocol?
Medicine® will consider study protocols for proposed or ongoing research (dates must be included in the manuscript). Articles that report work previously completed will not be considered.

Study protocols must have ethics and approval and funding in order to be considered (proof is required).

Registration is mandatory for any clinical trial. Approved registries for clinical trials need to meet all of the ICMJE Clinical Trial Registration guidelines. Trial Registration numbers will need to be included in the abstract.

What are the accepted funding agencies for study protocols?
Medicine® will currently only accept study protocols from approved funding agencies. The list of agencies is provided below.

Academy of Finland (Finland)
BIOTEC (Thailand)
California Institute for Regenerative Medicine (US)
Canadian Institutes of Health Research (Canada)
Centre National de la Recherche Scientifique (France)
Consejo Superior de Investigaciones Cientificas (Spain)
Consiglio Nazionale delle Ricerche (Italy)
Danmarks Grundforskningsfond (Denmark)
Deutsche Forschungsgemeinschaft (Germany)
FAPESP (Brazil)
Fondazione Telethon (Italy)
Fonds zur Forderung der wissenschaftlichen Forschung (Austria)
Fonds voor Wetenschappelijk Onderzoek (Belgium)
Health Research Board (Ireland)
Howard Hughes Medical Institute (US)
Indian Council of Medical Research (India)

INSERM (France)
International Human Frontier Science Program Organization (International)
Israel Science Foundation (Israel)
Japan Society for the Promotion of Science (Japan)
Max Planck Society (Germany)
Medical Research Council (UK)
Ministry of Education, Culture, Sports, Science and Technology (Japan)
National Health Service (UK)
National Institutes of Health (US)
National Natural Science Foundation of China (China)
National Research Foundation of Korea (Korea)
​National Science Foundation (US)
Natural Environment Research Council (UK)
Nederlandse Organisatie voor Wetenschappelijk Onderzoek (Netherlands)
Rockefeller Foundation (US)
South African Medical Research Council (South Africa)
Swedish Foundation for Strategic Research (Sweden)
Swedish Research Council (Sweden)
Swiss National Science Foundation (Switzerland)
Wellcome Trust (UK)

Does Medicine® consider unfunded study protocols for publication?
No. At this time Medicine® will not consider the publication of an unfunded study protocol.

Are study protocols fully-citable?
Yes. Study Protocols are fully-citable and will be available freely online.

What article type should I select when submitting a study protocol?
You will need to select Clinical Trial Protocol (SPIRIT Compliant) or Systematic Review and Meta-Analysis Study Protocol (PRISMA-P Complaiant) article types when submitting. All considerations must adhere to the SPIRIT or PRISMA-P EQUATOR guidelines and checklists. The checklists can be found under 'Files and Resources' on the Medicine® submission site.

Additional information regarding the EQUATOR guidelines can be found in the following sources:

What is the publication fee for study protocols?
Medicine® will charge an article publishing fee (APC) of $1050 to publish a Study Protocol under the CCBY license. Please be sure to select the proper license on the License to Publish form.