Study Protocol FAQ

​​​Why publish study protocols?
Study protocols provide a detailed blueprint for upcoming clinical trials and Medicine® believes publishing registered trials will help improve the standard of medical research. Study protocols enable more information to be available on current studies, while promoting collaboration and helping to prevent unnecessary duplication of work.

What are the criteria for publishing a study protocol?
Medicine® will consider study protocols for proposed or ongoing research (dates must be included in the manuscript). Articles that report work previously completed will not be considered.

Study protocols must have ethics and approval (if applicable). ​

Registration is mandatory for any clinical trial. Approved registries for clinical trials need to meet all of the ICMJE Clinical Trial Registration guidelines. Trial Registration numbers will need to be included in the abstract.

​Does Medicine® consider unfunded study protocols for publication?
No. At this time Medicine® will not consider the publication of an unfunded study protocol.

Are study protocols fully-citable?
Yes. Study Protocols are fully-citable and will be available freely online.

What article type should I select when submitting a study protocol?
You will need to select Clinical Trial Protocol (SPIRIT Compliant) or Systematic Review and Meta-Analysis Study Protocol (PRISMA-P Complaiant) article types when submitting. All considerations must adhere to the SPIRIT or PRISMA-P EQUATOR guidelines and checklists. The checklists can be found under 'Files and Resources' on the Medicine® submission site.

Additional information regarding the EQUATOR guidelines can be found in the following sources:

What is the publication fee for study protocols?
Medicine® will charge an article publishing fee (APC) of $1050 to publish a Study Protocol under the CCBY license. Please be sure to select the proper license on the License to Publish form.