Skip Navigation LinksHome > January 2011 - Volume 49 - Issue 1 > Effect of Standardized, Patient-Centered Label Instructions...
Medical Care:
doi: 10.1097/MLR.0b013e3181f38174
Brief Report

Effect of Standardized, Patient-Centered Label Instructions to Improve Comprehension of Prescription Drug Use

Wolf, Michael S. MA, MPH, PhD*†‡; Davis, Terry C. PhD§¶; Curtis, Laura M. MS†; Webb, Jennifer A. MA*†; Bailey, Stacy Cooper MPH*†; Shrank, William H. MD, MSHS∥; Lindquist, Lee MD, MPH*†; Ruo, Bernice MD*†; Bocchini, Mary V. BA§¶; Parker, Ruth M. MD**; Wood, Alastair J. J. MD††‡‡

Collapse Box

Abstract

Objective: To evaluate the effectiveness of standardized, patient-centered label (PCL) instructions to improve comprehension of prescription drug use compared with typical instructions.

Methods: A total of 500 adult patients recruited from 2 academic and 2 community primary care clinics in Chicago, IL and Shreveport, LA were assigned to receive as follows: (1) standard prescription instructions written as times per day (once, twice 3 times per day) (usual care), (2) PCL instructions that specify explicit timing with standard intervals (morning, noon, evening, bedtime) (PCL), or (3) PCL instructions with a graphic aid to visually depict dose and timing of the medication (PCL + Graphic). The outcome was correct interpretation of label instructions.

Results: Instructions with the PCL format were more likely to be correctly interpreted compared with standard instructions (adjusted relative risk [RR]: 1.33, 95% confidence interval [CI]: 1.25–1.41). Inclusion of the graphic aid (PCL + Graphic) decreased rates of correct interpretation compared with PCL instructions alone (RR: 0.93; 95% CI: 0.89–0.97). Patients with low literacy were better able to interpret PCL instructions (low literacy: RR: 1.39; 95% CI: 1.14–1.68; P = 0.001).

Conclusion: The PCL approach could improve patients' understanding and use of their medication regimen.

© 2011 Lippincott Williams & Wilkins, Inc.

Login

Article Tools

Share

Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.