Institutional members access full text with Ovid®

Share this article on:

Contemporary management and outcomes of blunt thoracic aortic injury: A multicenter retrospective study

DuBose, Joseph J. MD; Leake, Samuel S.; Brenner, Megan MD; Pasley, Jason MD; O’Callaghan, Thomas MD; Luo-Owen, Xian MD, PhD; Trust, Marc D. MD; Mooney, Jennifer MD; Zhao, Frank Z. MD; Azizzadeh, Ali MD; the Aortic Trauma Foundation

Journal of Trauma and Acute Care Surgery: February 2015 - Volume 78 - Issue 2 - p 360–369
doi: 10.1097/TA.0000000000000521
Original Articles
Editor's Choice

BACKGROUND: Blunt thoracic aortic injuries (BTAIs) are composed of a spectrum of lesions ranging from intimal tear to rupture, yet optimal management and ultimate outcome have not been clearly established.

METHODS: This is a retrospective multicenter study of BTAIs from January 2008 to December 2013. Demographics, diagnosis, treatment, and in-hospital outcomes were analyzed.

RESULTS: Nine American College of Surgeons–verified Level I trauma centers contributed data from 453 patients with BTAIs. After exclusion of patients expiring before imaging (58) and transfers (13), 382 patients with imaging diagnosis were available for analysis (Grade 1, 94; Grade 2, 68; Grade 3, 192; Grade 4, 28). Hypotension was present on admission in 56 (14.7%). Computed tomographic angiography was used for diagnosis in 94.5%. Nonoperative management (NOM) was selected in 32%, with two in-hospital failures (Grade 1, Grade 4) requiring endovascular salvage (thoracic endovascular aortic repair [TEVAR]). Open repair (OR) was completed in 61 (16%). TEVAR was conducted in 198 (52%), with 41% of these requiring left subclavian artery coverage. Complications of TEVAR included endograft malposition (6, 3.0%), endoleak (5, 2.5%), paralysis (1, 0.5%), and stroke (2, 1.0%). Six TEVAR failures were treated by repeat TEVAR (2) or OR (4). Overall in-hospital mortality was 18.8%, and aortic-related mortality was 6.5% (NOM, 9.8%; OR, 13.1%; TEVAR, 2.5%) (Grade 1, 0%; Grade 2, 2.9%; Grade 3, 5.2%; Grade 4, 46.4%). The majority of aortic-related deaths (18 of 25) occurred before the opportunity for repair. Independent predictors of aortic-related mortality among BTAI patients were higher chest Abbreviated Injury Scale (AIS) score, grade, and Injury Severity Score (ISS); TEVAR was protective (p = 0.03; odds ratio, 0.21; confidence interval, 0.05–0.88).

CONCLUSION: Failures and aortic-related mortality of NOM following BTAI Society of Vascular Surgery Grade 1 to 3 injuries are rare. TEVAR seems independently protective against aortic-related mortality. Early complications of TEVAR have decreased relative to previous reports. Prospective long-term follow-up data are required to better refine indications for intervention.

LEVEL OF EVIDENCE: Level IV.

From the University of Texas–Houston (J.J.D., S.S.L., C.M., A.A.), Houston; University of Texas Southwestern–Austin (M.D.T., C.V.R.B.), Austin; and University of Texas Southwestern–Dallas, Dallas, Texas; R Adams Cowley Shock Trauma Center (M.B., J.P., T.S.), University of Maryland, Baltimore, Maryland; Loma Linda University Medical Center (T.A.O., X.L.-O., C.D.), Loma Linda; and Los Angeles County + University of Southern California Hospital (O.R., K.I., D.D.), Los Angeles, California; Louisiana State University Health Sciences Center (J.M., W.M.), New Orleans, Louisiana; Mayo Clinic–Rochester (M.Z., M.Al., M.Am., D.J.), Rochester, New York; and University of Arizona School of Medicine (G.V., A.E.), Tucson, Arizona.

Submitted: August 24, 2014, Revised: November 4, 2014, Accepted: November 11, 2014.

Address for reprints: Lt Col Joe DuBose, MD, USAF, MC, 6400 Fannin St, Suite 2850, Houston, TX 77030; email: jjd3c@yahoo.com.

© 2015 Lippincott Williams & Wilkins, Inc.