We highlight three articles on very different aspects of lung cancer in the July issue of the Journal. As investigators and clinicians in lung cancer know, the very useful 7th edition of the TNM classification for lung cancer is still based on anatomical information. The ongoing work by the IASLC staging committee, which will culminate in the publication of the 8th edition, is evaluating other prognostic markers including histology, tumor markers and molecular genetic factors. The first highlighted article is from the IASLC staging committee and is authored by Rami-Porta and colleagues. “The IASLC Lung Cancer Staging Project: Proposals for the Revisions of the T Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Lung Cancer” discusses revisions of the T descriptors which will be included in the new edition of the TNM lung cancer classification. Hormone use and the risk of lung cancer in women continues to be an important area of research. Schwartz et al describes epidemiologic data on this subject in the article, “Hormone use, reproductive history and risk of lung cancer: the Women's Health Initiative Studies”. Finally, Koenig et al suggest that amplicon parallel sequencing improves the diagnostic accuracy of aberrant molecular events in NSCLC, in the article “Implementation of amplicon parallel sequencing leads to improvement of diagnosis and therapy of lung cancer patients”.
Alex A. Adjei, MD, PhD, Editor-in-Chief