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Polydactyly in the multiethnic Negev population at southern Israel

Yeshayahu, Yonatana,b; Sagi, Amiramc; Silberstein, Eldadc

Journal of Pediatric Orthopaedics B: May 2014 - Volume 23 - Issue 3 - p 274–276
doi: 10.1097/BPB.0000000000000039
Upper Limb

The objective of this study was to characterize the prevalence, ethnic mix, and associated malformations of polydactyly in a multiethnic population. A retrospective analysis of 189 polydactyly patients was carried out. The incidence of polydactyly was 0.5/1000 live births and was higher in the Bedouin population. Preaxial polydactyly was 10 times more prevalent in the Jewish population and sporadic, and postaxial polydactyly was more prevalent in the consanguineous Bedouin population and associated with other malformations. We conclude that the pathologies in embryogenesis leading to preaxial and postaxial polydactyly vary, with the former occurring sporadically compared with the latter, which predominates in consanguineous families and syndromes.

aPediatrics B Department, Sheba Medical Center, Safra Children’s Hospital, Tel-Hashomer

bDepartment of Pediatrics, Faculty of Medicine, Tel-Aviv University, Tel-Aviv

cDepartment of Plastic and Reconstructive Surgery, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva, Israel

Correspondence to Yonatan Yeshayahu, MD, MHA, Pediatrics B Department, Sheba Medical Center, Safra Children’s Hospital, 52621 Tel-Hashomer, Israel Tel: +972 3 5307113; fax: +972 3 5305055; e-mail: yonatan.yeshayahu@sheba.health.gov.il

© 2014 by Lippincott Williams & Wilkins, Inc.