Skip Navigation LinksHome > March 2013 - Volume 22 - Issue 2 > Conservative treatment of a pathological fracture in a 3-yea...
Text sizing:
Journal of Pediatric Orthopaedics B:
doi: 10.1097/BPB.0b013e32834fe880

Conservative treatment of a pathological fracture in a 3-year-old boy with primary hyperoxaluria type I

Dierselhuis, Edwin F.; Maathuis, Patrick G.M.

Collapse Box


Primary hyperoxaluria type I is a rare inherited disease that presents a disturbed metabolism of glyoxylate. Consequently, patients suffer from hyperoxaluria, leading to renal failure and subsequent skeletal calcium oxalate deposition. Areas with high concentrations of calcium oxalate, so-called dense metaphyseal bands, are at risk for pathological fracturing. The primary disease is treated by combined liver–kidney transplantation, although pathological fracturing also occurs in the posttransplant period. In the current case, we present a 3-year-old boy with a pathological fracture of his right femur, 2 years after liver–kidney transplantation. We opted for a conservative regime, leading to good fracture healing. As there are limited data in the literature regarding treatment of fractures in these patients, it is important to notify the outcome of conservative treatment of pathological fractures in patients with primary hyperoxaluria type I.

© 2013 Lippincott Williams & Wilkins, Inc.


Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.