Nonmetastatic extraocular retinoblastoma is a common entity in South-East Asia. We did a retrospective study of patients treated for isolated extraocular retinoblastoma, that is, International retinoblastoma staging system stages II and III, using a uniform chemotherapy protocol at our oncology center, between June 2003 and June 2008. Out of the 25 patients having nonmetastatic extraocular retinoblastoma, 6 were in stage II, and 19 in stage III. The probability of event-free survival was 0.54 at 18 months of follow-up with no significant difference between the 2 stages and the presence of optic nerve involvement; 11 out of 13 relapses were systemic. This is the largest case series of nonmetastatic extraocular retinoblastoma from South-East Asia.
*Department of Medical Oncology
§Oculoplastics and Ocular Oncology Service
¶Department of Radiotherapy
†B.R.A. Institute Rotary Cancer Hospital
∥Rajendra Prasad Centre for Ophthalmic Sciences
‡All India Institute of Medical Sciences, New Delhi, India
Reprints: Sameer Bakhshi, MD, Associate Professor of Pediatric Oncology, Department of Medical Oncology, Dr B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India (e-mail: firstname.lastname@example.org).
Received for publication June 26, 2009
accepted September 2, 2009
Supported by none.