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Journal of Pediatric Hematology/Oncology:
February 2004 - Volume 26 - Issue 2 - pp 112-115
Clinical and Laboratory Observations

Reactivation of the Bacille Calmette-Guerin Scar Following Immune Reconstitution During Treatment of Infant Acute Lymphoblastic Leukemia

Swinson, Sophie MA, MBBS, MRCPCH; Hall, Georgina PhD, FRCP, MRCPath; Pollard, Andrew J. MBBS FRCPCH PhD

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Abstract

The authors describe an infant presenting at 2 weeks of age with congenital acute lymphoblastic leukemia who had previously received routine bacille Calmette-Guérin (BCG) vaccination at birth. The risk of BCG dissemination in immunocompromised infants is discussed and the use of antimycobacterial prophylaxis in such cases considered.

© 2004 Lippincott Williams & Wilkins, Inc.

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