Skip Navigation LinksHome > May 2015 - Volume 37 - Issue 4 > Hydroa Vacciniforme-like Lymphoma: A Case Report From India
Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0000000000000221
Online Articles: Clinical and Laboratory Observations

Hydroa Vacciniforme-like Lymphoma: A Case Report From India

Boddu, Deepthi DNB*; George, Renu MD; Nair, Sheila MD; Bindra, Mandeep MD; G. Mathew, Leni MD, MRCPCH*

Collapse Box


We report a 14-year-old Indian boy who presented with a history of weight loss, fever, facial edema, and a relapsing papulovesicular eruption on the face and limbs for 1 year. Histopathology of the skin showed dense lymphoid infiltrate from dermis to subcutaneous fat. Immunohistochemistry of this lymphoid infiltrate was CD3+, CD8+, CD56+, CD57+, Granzyme B+, TIA+, and Epstein Barr virus LMP1+. The histopathology and immunohistochemistry were consistent with the diagnosis of hydroa vacciniforme-like T-cell lymphoma. The child responded remarkably to oral steroids but relapsed on tapering doses. CHOP (Cyclophosphamide, Adriamycin, Vincristine, and Prednisolone) chemotherapy was initiated in view of systemic involvement to which he showed some response, however, the disease relapsed again. He then had a rapidly progressive disease and ultimately succumbed to his illness. This is the first case of hydroa vacciniforme-like T-cell lymphoma being reported from this subcontinent.

Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.


Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.

Connect With Us


For additional oncology content, visit LWW Oncology Journals on Facebook.