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Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0000000000000233
Clinical and Laboratory Observations: PDF Only

Severe Anemia in an Adolescent Male With Sickle Cell Trait: A Case Report.

Chapa-Rodriguez, Adrian MD; Dighe, Dipti MD; Giordano, Lisa MD

Published Ahead-of-Print
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Abstract

Background: Sickle cell trait is generally considered a benign condition. However, it has been associated with uncommon comorbidities such as painless gross hematuria secondary to renal papillary necrosis and renal medullary carcinoma.

Observation: We present a 16-year-old African American boy with sickle cell trait and a recent history of prolonged gross hematuria due to renal papillary necrosis. The patient developed severe iron deficiency anemia and required transfusion support.

Conclusions: Although renal papillary necrosis is well-described, it is uncommon in pediatrics and only rarely results in the need for transfusion.

(C) 2014 by Lippincott Williams & Wilkins.

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