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Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0000000000000204
Clinical and Laboratory Observations: PDF Only

Massive Splenic Infarction and Portal Vein Thrombosis in Children With Chronic Myeloid Leukemia.

Aksu, Tekin MD; Erdem, Arzu Y. MD; Fettah, Ali MD; Kaçar, Dilek MD; Avci, Zekai MD; Yarali, Nese MD; Tunc, Bahattin MD

Published Ahead-of-Print
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Massive splenic infarction and portal vein thrombosis (PVT) due to chronic myeloid leukemia (CML) is extremely rare. We describe 2 children who were presented with massive splenic infarction and PVT in the course of CML. Massive splenic infarction and PVT treated with splenectomy in one and with medical treatment in another in whom PVT resolved by cytoreductive treatment, led to downsizing of spleen or splenectomy. Splenic infarct and PVT should be considered in CML patients with long-lasting severe abdominal pain despite appropriate medical attempts. Splenectomy should be spared for persistent symptoms and complications.

(C) 2014 by Lippincott Williams & Wilkins.


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