Immature Ovarian Teratoma: When to Give Adjuvant Therapy?Faure-Conter, Cécile MD*; Pashankar, Farzana MD†Journal of Pediatric Hematology/Oncology: October 2017 - Volume 39 - Issue 7 - p 487–489 doi: 10.1097/MPH.0000000000000950 Invited Review Abstract Author Information The question of giving or not adjuvant chemotherapy in pure ovarian immature teratomas (ITs) remains unsolved to date and illustrates differences in management between pediatric and adults oncologists. Because of the rarity of these tumors, this question has never been addressed through randomized trials. Standard of care for adult women with ovarian ITs is postoperative platinum based chemotherapy for all patients except FIGO stage IA, grade 1 tumors, whereas pediatric series concluded that surgery alone is curative for completely resected ovarian ITs, regardless of grade. Moreover the role of chemotherapy in incompletely resected tumors and its impact on the rate of malignant relapses needs to be better assessed. This emphasizes the urgent need for cooperation between adult and pediatric teams. *Department of Pediatrics, Institut d’Hemato-Oncologie Pediatrique, Lyon, France †Yale University School of Medicine, New Haven, CT The authors declare no conflict of interest. Reprints: Cécile Faure-Conter, MD, Department of Pediatrics, Institut d’Hémato-Oncologie Pédiatrique, 1 Place Joseph Renault, 69008 Lyon, France (e-mail: email@example.com). Received September 2, 2016 Accepted July 12, 2017 Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.