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Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e31827e5302
Clinical and Laboratory Observations

Inflammatory Myofibroblastic Tumors Following the Treatment of Malignancy in Childhood: Case Reports

Adamski, Jennifer K. MBChB, PhD, MD; Kelsey, Anna MBChB, FRCPATH, MD; Brennan, Bernadette MBChB, MD

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Abstract

Inflammatory myofibroblastic tumors (IMT) are rare, mostly benign soft tissue tumors. Occurring mainly in children the presentation, clinical features, and diagnostic dilemmas raised are well reported. Here we describe 4 patients diagnosed with IMT after the treatment of childhood cancer, and review the literature regarding IMT and malignancy. Discussing them in this context raises clinical questions; Are these tumors incidental or a consequence of treatment? Are they more common than we think and are any miss-diagnosed as tumor recurrence? This paper aims to raise awareness of IMT as diagnostic possibilities after treatment for childhood malignancies.

Copyright © 2013 by Lippincott Williams & Wilkins

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