Skip Navigation LinksHome > July 2013 - Volume 35 - Issue 5 > Mucoepidermoid Carcinoma of the Parotid as a Secondary Malig...
Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e3182468c55
Clinical and Laboratory Observations

Mucoepidermoid Carcinoma of the Parotid as a Secondary Malignancy After Chemotherapy in a Child With Neuroblastoma

Blatt, Julie MD*,†; Zdanski, Carlton MD; Scanga, Lori MD, PhD§; Rao, Kathleen W. PhD*,∥; Morris, David E. MD; Shockley, William W. MD

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Abstract

Secondary neoplasms are not reported frequently after neuroblastoma, which until recently was a cancer with limited long-term survival. Although salivary gland tumors in children and adolescents may be idiopathic, they are seen more often after head and neck radiation. We report a child with stage 4 neuroblastoma treated with high-dose multiagent chemotherapy without radiation therapy to his neck who, within 1 year of treatment, developed a low-grade but large and locally aggressive mucoepidermoid carcinoma of his parotid gland further characterized by a t(11;19)(q21;p13.1). Our patient extends the spectrum of secondary neoplasms after neuroblastoma.

Copyright © 2012 by Lippincott Williams & Wilkins

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