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Immune Thrombocytopenia in Children Less Than 1 Year of Age: A Single-institution 10-year Experience

Lo, Clara MD*; Wong, Wendy MD*; Glader, Bertil MD, PhD*,†; Jeng, Michael MD*

Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e3182580ab4
Clinical and Laboratory Observations
Abstract

Immune thrombocytopenia (ITP) in children less than one year of age is less well characterized compared to ITP in toddlers and school-age children. We performed a 10-year retrospective review of ITP patients in this age-cohort at our institution. Diagnosis and classification were made according to the 2009 International Working Group criteria. Fourteen infants were identified. Their bleeding scores were Grades 1 to 2 (79%), Grade 3 (22%), Grades 4 to 5 (0%). Eight patients received treatment with a 75% response rate. Three patients (21%) developed chronic ITP. These observations suggest that ITP in very young patients is similar to typical childhood ITP.

Author Information

Departments of *Pediatrics

Pathology, Stanford University School of Medicine, Palo Alto, CA

The authors declare no conflict of interest.

Reprints: Clara Lo, MD, Division of Pediatric Hematology/Oncology/Stem Cell Transplantation, 1000 Welch Road, Suite 300, Palo Alto, CA 94304 (e-mail: claralo@stanford.edu).

Received October 13, 2011

Accepted March 29, 2012

© 2013 by Lippincott Williams & Wilkins.