Skip Navigation LinksHome > January 2013 - Volume 35 - Issue 1 > Use of Gemcitabine With Multi-stage Surgical Resection as Su...
Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e3182707577
Online Articles: Clinical and Laboratory Observations

Use of Gemcitabine With Multi-stage Surgical Resection as Successful Second-line Treatment of Metastatic Pancreatoblastoma

Belletrutti, Mark J. MD*; Bigam, David MD; Bhargava, Ravi MD; Grundy, Paul MD*

Collapse Box

Abstract

Pancreatoblastoma is a rare pediatric pancreatic malignancy. It confers a worse prognosis if there is metastatic or unresectable disease. We report a case of a 12-year-old boy who presented with pancreatoblastoma of the head of the pancreas with multiple intrahepatic metastases. We successfully treated him using aggressive chemotherapy, multi-stage surgery, and gemcitabine chemotherapy, which has not been described as treatment for pancreatoblastoma. Rare childhood malignancies such as pancreatoblastoma require a coordinated, multidisciplinary approach and frequent reassessment of therapeutic interventions. Complete surgical resection is important for cure and may require complex, aggressive, multiple-stage surgical procedures with concurrent or novel chemotherapy.

© 2013 Lippincott Williams & Wilkins, Inc.

Login

Article Tools

Share

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.

Connect With Us

Twitter
twitter.com/JPHOonline

For additional oncology content, visit LWW Oncology Journals on Facebook.