Skip Navigation LinksHome > January 2013 - Volume 35 - Issue 1 > Probable Cytarabine-induced Acral Erythema: Report of 2 Ped...
Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e3182580ba0
Online Articles: Clinical and Laboratory Observations

Probable Cytarabine-induced Acral Erythema: Report of 2 Pediatric Cases

Ozmen, Serap MD*; Dogru, Mahmut MD*; Bozkurt, Ceyhun MD; Kocaoglu, Ayse Ceyda MD

Collapse Box

Abstract

Acral erythema (palmoplantar erythrodysesthesia) is a localized skin side effect that is seen most often in patients receiving cytarabine, liposomal pegylated doxorubicin, capecitabine, and 5-fluorouracil. It is characterized by painful erythema of both palms and soles with symmetrically well-defined borders, which may progress to bullae formation and desquamation. It is frequently occurred in patients with acute myeloid leukemia and lymphoma. Here, we reported 2 cases of acral erythema that developed during cytarabin-etoposide and cytarabine-mitoxantrone combination treatment for acute myeloid leukemia. Although rarely reported in children, pediatricians should especially be aware of this reaction when taking care of children who receive chemotherapy.

© 2013 Lippincott Williams & Wilkins, Inc.

Login

Article Tools

Share

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.

Connect With Us

Twitter
twitter.com/JPHOonline

For additional oncology content, visit LWW Oncology Journals on Facebook.