We compared DXA whole body and lumbar spine bone mineral density (BMD) using manufacturers software with a body size correction which derived bone mineral content (BMC) for bone area in survivors of acute lymphoblastic leukemia in Saudi Arabia (n=51, mean age 13.5 y). With no corrections, 29 patients (57%) had lumbar spine BMD Z score <−1.0 and 21 (41%) had whole body BMD Z score <−2. After correction, only 6 (12%) had lumbar spine BMC Z score <−1.0 and 4 (8%) had whole body BMC Z score <−2. Agreement between the methods was “poor” by weighted κ analysis.
*College of Medical, Veterinary, and Life Sciences, University of Glasgow
‡Bone and Endocrine Research Group, Royal Hospital for Sick Children
§School of Psychological Sciences and Health, University of Strathclyde, Glasgow, Scotland
†King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia
Supported by Al Majma’ah University and the Scottish Funding Council.
The authors declare no conflict of interest.
Reprints: John J. Reilly, PhD, School of Psychological Sciences and Health, University of Strathclyde, Glasgow G13 1PP, Scotland (e-mail: firstname.lastname@example.org).
Received December 4, 2011
Accepted March 28, 2012