Skip Navigation LinksHome > January 2013 - Volume 35 - Issue 1 > Importance of Adjusting Dual-energy X-Ray Output for Body Si...
Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e3182678ed8
Online Articles: Clinical and Laboratory Observations

Importance of Adjusting Dual-energy X-Ray Output for Body Size: An Example From Survivors of Childhood Acute Lymphoblastic Leukemia

Aldhafiri, Fahad MSc*; Al-Nasser, Abdallah MB, ChB; Al-Sugair, Abdulaziz MB ChB; Khanna, Sheila PhD; Ahmed, Faisal S. MD, MRCPCH; Al-Mutairi, Hanan RD; Reilly, John J. PhD*,§

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Abstract

We compared DXA whole body and lumbar spine bone mineral density (BMD) using manufacturers software with a body size correction which derived bone mineral content (BMC) for bone area in survivors of acute lymphoblastic leukemia in Saudi Arabia (n=51, mean age 13.5 y). With no corrections, 29 patients (57%) had lumbar spine BMD Z score <−1.0 and 21 (41%) had whole body BMD Z score <−2. After correction, only 6 (12%) had lumbar spine BMC Z score <−1.0 and 4 (8%) had whole body BMC Z score <−2. Agreement between the methods was “poor” by weighted κ analysis.

© 2013 Lippincott Williams & Wilkins, Inc.

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