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Skip Navigation LinksHome > August 2012 - Volume 34 - Issue 6 > t(6;9)(p23;q34) Presenting Acute Myeloid Leukemia in a Child...
Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e318238866f
Online Articles: Clinical and Laboratory Observations

t(6;9)(p23;q34) Presenting Acute Myeloid Leukemia in a Child With an Unsuspected 45,X/46,X,derY [?t(Yp;Yq)] Chromosomal Constitution: Yet Another Y Chromosome Overdosage and Malignancy Association

Ogur, Gönül MD*; Duru, Feride MD; Ozyurek, Emel MD; Fisgin, Tunc MD

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Abstract

Development of leukemia in patients with sexual chromosome abnormalities is relatively rare and mostly involves cases of monosomy X, Turner syndrome. Here, we report on a child having a 45,X/46,X,derY [?t(Yp;Yq)] chromosomal constitution (variant Turner syndrome) presenting with concordant acute myeloid leukemia and a rarely seen clonal neoplasic cell lineage-related karyotype, t(6;9)(p23;q34).

© 2012 Lippincott Williams & Wilkins, Inc.

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