Skip Navigation LinksHome > August 2012 - Volume 34 - Issue 6 > Scurvy in a Child With Autism: Magnetic Resonance Imaging a...
Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e318236c519
Radiology Corner

Scurvy in a Child With Autism: Magnetic Resonance Imaging and Pathological Findings

Niwa, Tetsu MD*; Aida, Noriko MD*; Tanaka, Yukichi MD; Tanaka, Mio MD; Shiomi, Masae MD; Machida, Jiro MD§

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We present a case of scurvy in a 6-year-old boy with autism and an unbalanced diet. The patient was admitted with difficulties in walking. Magnetic resonance imaging findings of the thigh showed diffuse signal abnormality in the bone marrow, periosteum, and the femoral muscle. A biopsy specimen of the femur showed hematoma, proliferative fibroblasts, and few collagen fibers, which suggested a deficiency of vitamin C. Although recurrent periosteal hematoma may be suggestive of scurvy, this finding was subtle in the current case. It is important to be aware of this rare disease because it is easily cured with vitamin C supplementation.

© 2012 Lippincott Williams & Wilkins, Inc.


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