Home Current Issue Previous Issues Publish Ahead-of-Print Collections For Authors Journal Info
Skip Navigation LinksHome > August 2012 - Volume 34 - Issue 6 > Acute Monoblastic Leukemia That Switched Lineage at Relapse...
Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e318233219d
Online Articles: Clinical and Laboratory Observations

Acute Monoblastic Leukemia That Switched Lineage at Relapse to Acute Lymphoblastic Leukemia: A Case Report

Inoue, Akiko MD, PhD*; Kawakami, Chihiro*; Takitani, Kimitaka*; Ikemoto, Toshiyuki; Tamai, Hiroshi*

Collapse Box

Abstract

We herein present the case of an acute monoblastic leukemia infant who relapsed with acute lymphoblastic leukemia (ALL). Complete remission was achieved after an acute myeloblastic leukemia-directed chemotherapy, but the patient relapsed with pro-B ALL. As he did not respond to acute myeloblastic leukemia-type reinduction therapy, he was switched to ALL-type chemotherapy, and a complete remission was achieved. Unrelated cord blood stem cell transplantation was performed, but he relapsed with pro-B ALL again. After he received ALL-type chemotherapy, he underwent another bone marrow transplant from his human leukocyte antigen mismatch mother, and has been free from recurrence for over 8 months.

© 2012 Lippincott Williams & Wilkins, Inc.

Login

Article Tools

Share

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.

Connect With Us

Twitter
twitter.com/JPHOonline

For additional oncology content, visit LWW Oncology Journals on Facebook.