Acute Monoblastic Leukemia That Switched Lineage at Relapse to Acute Lymphoblastic Leukemia: A Case ReportInoue, Akiko MD, PhD; Kawakami, Chihiro; Takitani, Kimitaka; Ikemoto, Toshiyuki; Tamai, HiroshiJournal of Pediatric Hematology/Oncology: August 2012 - Volume 34 - Issue 6 - p e258–e260 doi: 10.1097/MPH.0b013e318233219d Online Articles: Clinical and Laboratory Observations Abstract Author Information We herein present the case of an acute monoblastic leukemia infant who relapsed with acute lymphoblastic leukemia (ALL). Complete remission was achieved after an acute myeloblastic leukemia-directed chemotherapy, but the patient relapsed with pro-B ALL. As he did not respond to acute myeloblastic leukemia-type reinduction therapy, he was switched to ALL-type chemotherapy, and a complete remission was achieved. Unrelated cord blood stem cell transplantation was performed, but he relapsed with pro-B ALL again. After he received ALL-type chemotherapy, he underwent another bone marrow transplant from his human leukocyte antigen mismatch mother, and has been free from recurrence for over 8 months. *Department of Pediatrics †Department of Laboratory Medicine, Osaka Medical College, Takatsuki Japan The authors declare no conflict of interest. Reprints: Akiko Inoue, MD, PhD, Department of Pediatrics, Osaka Medical College, 2-7, Daigakumachi, Takatsuki, Osaka 569-8686, Japan (e-mail: email@example.com). Received June 10, 2011 Accepted August 16, 2011 Copyright © 2012 Wolters Kluwer Health, Inc. All rights reserved.