Skip Navigation LinksHome > August 2010 - Volume 32 - Issue 6 > Moyamoya in a Child Treated With Interferon for Recurrent Os...
Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e3181e5e1db
Clinical and Laboratory Observations

Moyamoya in a Child Treated With Interferon for Recurrent Osteosarcoma

Buchbinder, David MD, MSHS*; Steinberg, Gary MD, PhD; Linetsky, Michael MD; Casillas, Jacqueline MD, MSHS§

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Abstract

Moyamoya is a cerebral vasculopathy of unknown etiology rarely described as a late effect after the treatment of childhood cancer. We describe a 12-year-old female who developed moyamoya after the completion of systemic chemotherapy, surgery, and adjuvant interferon α for osteosarcoma with pulmonary metastases. Given the importance of characterizing late effects after the treatment of childhood cancer, the potential role of interferon α in the development of moyamoya is discussed.

© 2010 Lippincott Williams & Wilkins, Inc.

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