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Metastatic Primary Angiosarcoma of the Breast in a Pediatric Patient With a Complete Response to Systemic Chemotherapy and Definitive Radiation Therapy: Case Report and Review of the Literature

Gatcombe, Heather G. MD*; Olson, Thomas A. MD; Esiashvili, Natia MD*

Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e3181ca9ed7
Original Articles

We present a case of a rare malignancy, primary breast angiosarcoma, in a 15-year-old girl. She presented with a locally advanced tumor and suspected metastatic disease to the mediastinum and bones on PET imaging. The patient was treated with systemic chemotherapy and definitive radiation therapy to her left breast and achieved a complete response. She has no evidence of disease recurrence 44 months from her initial diagnosis.

Author Information

Departments of *Radiation Oncology, Emory University School of Medicine and Emory Winship Cancer institute

Pediatric Hematology/Oncology, Aflac Cancer Center and Blood Disorders Service, Children's Healthcare of Atlanta at Egleston, Atlanta, GA

Reprints: Heather G. Gatcombe, MD, Department of Radiation Oncology, Emory University School of Medicine and Emory Winship Cancer Institute, 1365 Clifton Road, NE, Atlanta, GA 30322 (e-mail:

Received for publication May 15, 2009; accepted November 11, 2009

© 2010 Lippincott Williams & Wilkins, Inc.