We present a case of a rare malignancy, primary breast angiosarcoma, in a 15-year-old girl. She presented with a locally advanced tumor and suspected metastatic disease to the mediastinum and bones on PET imaging. The patient was treated with systemic chemotherapy and definitive radiation therapy to her left breast and achieved a complete response. She has no evidence of disease recurrence 44 months from her initial diagnosis.
Departments of *Radiation Oncology, Emory University School of Medicine and Emory Winship Cancer institute
†Pediatric Hematology/Oncology, Aflac Cancer Center and Blood Disorders Service, Children's Healthcare of Atlanta at Egleston, Atlanta, GA
Reprints: Heather G. Gatcombe, MD, Department of Radiation Oncology, Emory University School of Medicine and Emory Winship Cancer Institute, 1365 Clifton Road, NE, Atlanta, GA 30322 (e-mail: firstname.lastname@example.org).
Received for publication May 15, 2009; accepted November 11, 2009