Skip Navigation LinksHome > March 2009 - Volume 31 - Issue 3 > Posterior Fossa Neoplasm and PHACES Syndrome: A Case Report
Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e3181983b15
Clinical and Laboratory Observations

Posterior Fossa Neoplasm and PHACES Syndrome: A Case Report

Wallen, Katharine E. MD*; Hadar, Eldad J. MD; Perry, Victor MD; Bouldin, Thomas W. MD; Loehr, James MD§; Blatt, Julie MD*

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A 4-year-old girl with PHACES syndrome (posterior fossa brain malformations, hemangiomas, arterial anomalies, cardiac anomalies/coarctation of the aorta, eye abnormalities, and sternal clefting/supraumbilical raphe) developed a cerebellar pilocytic astrocytoma 18 months after resolution of her neck, ear, and thoracic hemangiomas. Because cutaneous hemangiomas may have involuted by the time a patient is diagnosed with a central nervous system neoplasm, it seems possible that in other such patients the association may have gone unrecognized. Cerebellar pilocytic astrocytoma may be a rare manifestation of the posterior fossa malformations of PHACES.

© 2009 Lippincott Williams & Wilkins, Inc.


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