Skip Navigation LinksHome > July 2008 - Volume 30 - Issue 7 > Paraspinal Synovial Sarcoma as an Unusual Postradiation Comp...
Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e31816e22e3
Clinical and Laboratory Observations

Paraspinal Synovial Sarcoma as an Unusual Postradiation Complication in Pediatric Abdominal Neuroblastoma

Mullah-Ali, Ali FRCPC*; Ramsay, Jennifer A. MDCM, FRCP; Bourgeois, Jacqueline M. MSc, MD, FRCP; Hodson, Ian MA, BM, BCh, FRCPC; MacDonald, Paula BSc, Phm§; Midia, Mehran MD, FRCPC; Portwine, Carol MD, FRCPC, PhD*

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Abstract

The development of a soft-tissue sarcoma is an infrequent but well-known long-term complication of radiotherapy. Malignant fibrous histiocytomas, extraskeletal osteosarcomas, fibrosarcomas, malignant peripheral nerve sheath tumors, and angiosarcomas are most frequently encountered. Radiation-associated synovial sarcomas are uncommon and exceedingly rare in pediatric patients. We report an unusual case of paraspinal synovial sarcoma presenting in an adolescent female 13 years after radiation therapy for her neuroblastoma.

© 2008 Lippincott Williams & Wilkins, Inc.

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