Skip Navigation LinksHome > July 2008 - Volume 30 - Issue 7 > Metastatic Hepatic Epithelioid Hemangioendothelioma in a Tee...
Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e31816e22d1
Clinical and Laboratory Observations

Metastatic Hepatic Epithelioid Hemangioendothelioma in a Teenage Girl

Kassam, Alisha BEng, MD*; Mandel, Karen MD, FRCPC

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Hepatic epithelioid hemangioendothelioma (HEHE) is a rare malignant tumor characterized by its epithelioid structure and vascular endothelium origin. The clinical course of HEHE is variable, ranging from long-term survival without treatment to a rapidly progressive course with a fatal outcome. As a consequence, no standard treatment has been determined. We present a case of HEHE occurring in a 13-year-old girl, in which a novel treatment approach using antiangiogenic therapy was tried and was successful in slowing the progression of the disease.

© 2008 Lippincott Williams & Wilkins, Inc.


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