Skip Navigation LinksHome > July 2008 - Volume 30 - Issue 7 > A 13-year-old Girl With Cold Agglutinin Syndrome Caused by A...
Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e318161a9f9
Clinical and Laboratory Observations

A 13-year-old Girl With Cold Agglutinin Syndrome Caused by Anti-i

Mason, Holli M. MD*; Arndt, Patricia A. MSMT, MT(ASCP)SBB

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A 13-year-old girl with cold agglutinin syndrome caused by anti-i was serologically positive for Epstein-Barr virus. The anti-i had a high titer at 4°C and high thermal amplitude (reacting up to 37°C with both cord i RBCs and the patient's autologous RBCs). The patient's hemoglobin dropped to 48 g/L. The age of the patient, the severity of the hemolysis, and the antibody specificity were unusual features of cold agglutinin syndrome. Transfusions with adult (I) red blood cells were effective.

© 2008 Lippincott Williams & Wilkins, Inc.


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